Article
Molecular characterization of postnatal development of testicular steroidogenesis in luteinizing hormone receptor knockout mice.
Endocrinology - 1 Mar 2004
Zhang Fu-Ping, Pakarainen Tomi, Zhu Fei, Poutanen Matti, Huhtaniemi Ilpo
Abstract excerpt
We recently demonstrated that the sexual development of LH receptor (LHR) knockout mice is normal until birth, but is totally arrested thereafter. To study further the functional defects of LHR knockout mice, the expression of selected Leydig cell-specific genes was studied in (-/-) and control (...
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