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Article

Failure of normal adult Leydig cell development in androgen-receptor-deficient mice

1 Sept 2002

Abstract excerpt

During testicular development, fetal and adult populations of Leydig cells arise sequentially. Previous studies have shown that androgen action is required for normal steroidogenic activity in the mouse testis. Therefore, to determine the role of androgens in regulating fetal and adult Leydig cell differentiation and function, Leydig development has been measured in mice lacking functional androgen receptors...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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Identifiers

PMID: 12154079
DOI: 10.1242/jcs.115.17.3491

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