Article
Pattern of messenger ribonucleic acid expression of tissue inhibitors of metalloproteinases (TIMPs) during testicular maturation in male mice lacking a functional TIMP-1 gene.
Biology of reproduction - 1 Aug 1998
Nothnick W B, Soloway P D, Curry T E
Abstract excerpt
It has been proposed that proteolytic remodeling of the testicular extracellular matrix (ECM) plays a fundamental role in testicular development, morphogenesis, and spermatogenesis. Tissue inhibitor of metalloproteinase (TIMP)-1 regulates ECM turnover and has been reported to stimulate Leydig cel...
Topics
- Aging
- Animals
- Blotting, Northern
- Genotype
- Male
- Mice
- RNA, Messenger
- Sexual Maturation
- Testis
- Testosterone
- Tissue Inhibitor of Metalloproteinase-1
- Tissue Inhibitor of Metalloproteinases