Article
Binding and functional characteristics of two E-box motifs within the S100A6 (calcyclin) gene promoter.
Journal of cellular biochemistry - 1 Apr 2006
Leśniak Wiesława, Kuźnicki Jacek
Abstract excerpt
S100A6 (calcyclin) is a small calcium-binding protein of the S100 family often associated with cancer and metastasis. We have previously shown that the E-box sequence at position -283/-278 of the S100A6 gene promoter interacts with USF transcription factor and contributes to promoter transcriptional activity. We now present evidence that a second E-box motif at position -593/-588 of the promoter also binds USF...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
