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Article

Validation of dHPLC for molecular diagnosis of beta-thalassemia in Southern Italy.

Genetic testing - 1 Jan 2003

Colosimo Alessia, Guida Valentina, Scolari Anna, De Luca Alessandro, Palka Giandomenico, Rigoli Luciana, Meo Anna, Salpietro Damiano Carmelo, Dallapiccola Bruno

Abstract excerpt

Beta-thalassemia, the most common hereditary anemia in the Mediterranean area, results from over 200 causative mutations in the beta-globin locus. The aim of this study was to validate a denaturing high-performance liquid chromatography (dHPLC)-based assay for postnatal and prenatal molecular dia...

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Source

Identifiers

PMID: 14642006
DOI: 10.1089/109065703322537322

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14642006-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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