Article
The association between the genetic polymorphism of HLA-DQA1, DQB1, and DRB1 and serum alanine aminotransferase levels in chronic hepatitis C in the Chinese population.
Journal of gastroenterology and hepatology - 1 Sept 2008
Yu Rong-Bin, Hong Xin, Ding Wei-Liang, Tan Yong-Fei, Zhang Yong-Xiang, Sun Nan-Xiong, Wu Guan-Ling, Zhan Sheng-Wei, Ge Da-Fang
Abstract excerpt
BACKGROUND AND AIM: To investigate a possible association between HLA genes with serum alanine aminotransferase (ALT) levels and evaluate whether the HLA-DQA1, DQB1, and DRB1 genes could influence the development of liver damage in chronic hepatitis C. METHODS: A total of 145 patients with chronic hepatitis C virus (HCV) infection (36 patients with persistently normal ALT values; 109 patients with elevated ALT...
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