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Renal abnormalities in mice caused by insufficiency of p38alpha.

Journal of receptor and signal transduction research - 1 Jan 2003

Maruyama Masumi, Yagasaki Yuki, Sudo Tatsuhiko, Osada Hiroyuki

Abstract excerpt

p38MAP kinase (p38) is activated by hypertonicity and has been implicated to play a pivotal role in the renal system in survival under hypertonic conditions, both in vitro and in vivo. Although there are many aspects of the molecular events via the p38 pathway, its contribution to renal physiology and pathophysiology remains unclear. To elucidate the physiological relevance of p38 in renal function, we performed...

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Animals
Blood Urea Nitrogen
Body Weight
Creatinine
Drinking
Female
Fibrosis
Genotype
Kidney
Male
Mice
Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Knockout

Mitogen-Activated Protein Kinase 14

Mitogen-Activated Protein Kinases

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PMID: 14626445
DOI: 10.1081/rrs-120025197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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