Article
Role of the Nh (Non-hair) mutation in the development of dermatitis and hyperproduction of IgE in DS-Nh mice.
Experimental animals - 1 Oct 2003
Watanabe Akira, Takeuchi Mitsuo, Nagata Masafumi, Nakamura Kazuichi, Nakao Hiroyuki, Yamashita Hirofumi, Makino Susumu, Harada Minoru, Hirasawa Tsutomu
Abstract excerpt
The DS-Nh (DS Non-hair) mouse is a spontaneous hairless mutant of the DS mouse. The inheritance mode of the Nh mutation is autosomal dominant, and the Nh locus is mapped to Chromosome 11. The roles of the Nh mutation in spontaneous dermatitis and IgE hyperproduction were studied using an Nh conge...
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