Article
A new mutant hairless mouse with lymph node hyperplasia and late onset of autoimmune pathology.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Oct 1994
Massironi S M, Dagli M L, Lima M R, Alvarez J M, Kipnis T L
Abstract excerpt
Adult BALB/c male mice were injected with a single dose of ethyl nitroso urea (ENU; 250 mg/kg, i.p.) and mated to C57BL/6, DBA/2 and A/J adult females 13 weeks later. F1 males were mated with BALB/c females and F2 females were than backcrossed to the F1 parents. One BALB/c male mouse thus treated...
Topics
- Animals
- Autoimmune Diseases
- Castleman Disease
- Female
- Male
- Mice
- Mice, Hairless
- Mutation
- Phenotype
- Time Factors