Article
A new mutant hairless mouse with lymph node hyperplasia and late onset of autoimmune pathology.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Oct 1994
Massironi S M, Dagli M L, Lima M R, Alvarez J M, Kipnis T L
Abstract excerpt
Adult BALB/c male mice were injected with a single dose of ethyl nitroso urea (ENU; 250 mg/kg, i.p.) and mated to C57BL/6, DBA/2 and A/J adult females 13 weeks later. F1 males were mated with BALB/c females and F2 females were than backcrossed to the F1 parents. One BALB/c male mouse thus treated gave origin to a mutant presenting hair and skin alterations similar to those of natural hairless mutants. The new...
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