Article
-308 Nco I polymorphism of tumour necrosis factor alpha in overweight Caucasians.
Diabetes research and clinical practice - 1 Dec 2003
Morris Alison M, Heilbronn Leonie K, Noakes Manny, Kind Karen L, Clifton Peter M
Abstract excerpt
We investigated whether a polymorphism in the promoter region of the TNFalpha gene (-308 A/G) is associated with reduced weight loss in obese Australian subjects on an energy restricted diet. 189 healthy subjects and 91 subjects with type II diabetes were genotyped for the -308 Nco I polymorphism using PCR-RFLP techniques. A subset of these subjects (211 females and 45 males), were placed on a 30% energy...
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