Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered excitability of motor neurons in a transgenic mouse model of familial amyotrophic lateral sclerosis.

Neuroscience letters - 20 Nov 2003

Pieri Massimo, Albo Federica, Gaetti Chiara, Spalloni Alida, Bengtson C Peter, Longone Patrizia, Cavalcanti Silvio, Zona Cristina

Abstract excerpt

Various evidence suggests that amyotrophic lateral sclerosis (ALS) selectively affects motor neuron functioning, but electrophysiological alterations of single motor neurons in ALS remains to be documented. In the present work, the excitability of motor neurons has been tested in a transgenic mou...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Action Potentials
Share to Amyotrophic Lateral Sclerosis
Share to Disease Models, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Transgenic

Share to Motor Neurons

Share to Superoxide Dismutase

Share to Superoxide Dismutase-1

Source

Identifiers

PMID: 14623129
DOI: 10.1016/j.neulet.2003.07.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-14623129-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Altered excitability of motor neurons in a transgenic mouse model of familial amyotrophic lateral sclerosis.PMID 14623129Read ↗

Voltage-dependent sodium channels in spinal cord motor neurons display rapid recovery from fast inactivation in a mouse model of amyotrophic lateral sclerosis.Semantic proximity Read ↗

Excitability properties of mouse motor axons in the mutant SOD1(G93A) model of amyotrophic lateral sclerosis.Semantic proximity Read ↗

Intrinsic properties of lumbar motor neurones in the adult G127insTGGG superoxide dismutase‐1 mutant mouse in vivo: evidence for increased persistent inward currentsSemantic proximity Read ↗

Increased persistent Na(+) current and its effect on excitability in motoneurones cultured from mutant SOD1 mice.Semantic proximity Read ↗

Depressed excitability and ion currents linked to slow exocytotic fusion pore in chromaffin cells of the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.Semantic proximity Read ↗

Progressive motor neuron impairment in an animal model of familial amyotrophic lateral sclerosisSemantic proximity Read ↗

Adult spinal motoneurones are not hyperexcitable in a mouse model of inherited amyotrophic lateral sclerosis.Semantic proximity Read ↗

Early excitability changes in lumbar motoneurons of transgenic SOD1G85R and SOD1G(93A-Low) mice.Semantic proximity Read ↗

Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons.Semantic proximity Read ↗

Altered postnatal maturation of electrical properties in spinal motoneurons in a mouse model of amyotrophic lateral sclerosis.Semantic proximity Read ↗

Upregulation of persistent sodium conductances in familial ALSSemantic proximity Read ↗

Neurophysiological alterations in the nucleus reuniens of a mouse model of Alzheimer’s diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.