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Diverse Effects of Methylseleninic Acid on the Transcriptional Program of Human Prostate Cancer Cells

18 Nov 2003

Abstract excerpt

Methylseleninic acid (MSA) has been shown to have potent anticancer activity and is an excellent compound for studying the anticancer effects of selenium in vitro. To gain insights into the effects of MSA in prostate cancer, we characterized the global transcriptional response of LNCaP, an androgen-sensitive human prostate cancer cell line, to MSA by using high-density cDNA microarrays. We identified 951 genes...

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Share to Antioxidant Activity and Oxidative Stress
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PMID: 14617803
DOI: 10.1091/mbc.e03-07-0501

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