Article
Transformation of Streptococcus pneumoniae relies on DprA‐ and RecA‐dependent protection of incoming DNA single strands
27 Aug 2003
Abstract excerpt
Seventy-five years after the discovery of transformation with Streptococcus pneumoniae, it is remarkable how little we know of the proteins that interact with incoming single strands in the early processing of transforming DNA. In this work, we used as donor DNA in transformation a radioactively labelled homologous fragment to examine the fate of the single-stranded (ssDNA) products of uptake in cells mutant for...
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