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Article

Familial haemolytic uraemic syndrome and an MCP mutation.

Lancet (London, England) - 8 Nov 2003

Noris Marina, Brioschi Simona, Caprioli Jessica, Todeschini Marta, Bresin Elena, Porrati Francesca, Gamba Sara, Remuzzi Giuseppe

Abstract excerpt

BACKGROUND: Mutations in factor H (HF1) have been reported in a consistent number of diarrhoea-negative, non-Shiga toxin-associated cases of haemolytic uraemic syndrome (D-HUS). However, most patients with D-HUS have no HF1 mutations, despite decreased serum concentrations of C3. Our aim, therefore, was to assess whether genetic abnormalities in other complement regulatory proteins are involved. METHODS: We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 14615110
DOI: 10.1016/S0140-6736(03)14742-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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