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Article

Characterization of the human type XVIII collagen gene and proteolytic processing and tissue location of the variant containing a frizzled motif.

Matrix biology : journal of the International Society for Matrix Biology - 1 Sept 2003

Elamaa Harri, Snellman Anne, Rehn Marko, Autio-Harmainen Helena, Pihlajaniemi Taina

Abstract excerpt

Human type XVIII collagen was found to be expressed as three variants, termed NC1-303, NC1-493 and NC1-728, differing in their N-terminal non-collagenous domains (NC1). The corresponding gene was found to be approximately 105 kb in size and contain 43 exons. The short variant is derived from utilization of an upstream promoter associated with the first two exons of the gene. The two other variants are derived...

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PMID: 14614989
DOI: 10.1016/s0945-053x(03)00073-8

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