Article
Glycyrrhizin enhances interleukin-10 production by liver dendritic cells in mice with hepatitis.
Journal of gastroenterology - 1 Jan 2003
Abe Masanori, Akbar Fazle, Hasebe Aki, Horiike Norio, Onji Morikazu
Abstract excerpt
BACKGROUND: Glycyrrhizin (GL), an aqueous extract of licorice root, is known to have various immune-modulating and biological response-modifier activities. GL is used in patients with hepatitis to reduce the activity of liver inflammation; however, the mechanism underlying the anti-inflammatory activity of GL is poorly understood. As antigen-presenting dendritic cells (DC) in the tissue play a major role in the...
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