Article
CENP-B interacts with CENP-C domains containing Mif2 regions responsible for centromere localization.
The Journal of biological chemistry - 13 Feb 2004
Suzuki Nobutaka, Nakano Megumi, Nozaki Naohito, Egashira Shin-ichiro, Okazaki Tuneko, Masumoto Hiroshi
Abstract excerpt
Recently, human artificial chromosomes featuring functional centromeres have been generated efficiently from naked synthetic alphoid DNA containing CENP-B boxes as a de novo mechanism in a human cultured cell line, but not from the synthetic alphoid DNA only containing mutations within CENP-B boxes, indicating that CENP-B has some functions in assembling centromere/kinetochore components on alphoid DNA. To...
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