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Article

[Activation of transcription factors induced by low concentration of N-methyl-N'-nitro-N-nitrosoguanidine].

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences - 1 Oct 2003

Wang Gu-liang, Wang Zheng, Yang Jun, Yu Ying-nian

Abstract excerpt

OBJECTIVE: To investigate the effect of MNNG on some of the transcription factors such as NF- kappaB, CREB, AP-1 and c-Myc. METHODS: The activities of these transcription factors were measured by transient transfection assay of SEAP vectors. RESULT: The expressions of AP-1, CREB and NF- kappaB driven reporter genes were elevated for about 1.3, 1.4 and 1.3 times in MNNG-treated cells, respectively, as compared to...

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PMID: 14610736
DOI: 10.3785/j.issn.1008-9292.2003.05.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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