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Article

Residue Leu940 has a crucial role in the linkage and reaction specificity of the glucansucrase GTF180 of the probiotic bacterium Lactobacillus reuteri 180.

The Journal of biological chemistry - 21 Nov 2014

Meng Xiangfeng, Dobruchowska Justyna M, Pijning Tjaard, López Cesar A, Kamerling Johannis P, Dijkhuizen Lubbert

Abstract excerpt

Highly conserved glycoside hydrolase family 70 glucansucrases are able to catalyze the synthesis of α-glucans with different structure from sucrose. The structural determinants of glucansucrase specificity have remained unclear. Residue Leu(940) in domain B of GTF180, the glucansucrase of the probiotic bacterium Lactobacillus reuteri 180, was shown to vary in different glucansucrases and is close to the +1...

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Identifiers

PMID: 25288798
DOI: 10.1074/jbc.M114.602524
PMCID: PMC4239627

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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