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Article

Variation in the TNF gene promoter and risk of osteolysis after total hip arthroplasty.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Nov 2003

Wilkinson J Mark, Wilson A Gerard, Stockley Ian, Scott Ian R, Macdonald David A, Hamer Andrew J, Duff Gordon W, Eastell Richard

Abstract excerpt

UNLABELLED: Genetic factors may influence implant failure caused by osteolysis after THA. In an association study of 481 subjects after THA, we found that carriage of the TNF-238A allele was associated with an increased incidence of osteolysis versus noncarriage (odds ratio, 1.7) and was independ...

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Share to Arthroplasty, Replacement, Hip
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 14606512
DOI: 10.1359/jbmr.2003.18.11.1995

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14606512-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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