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Article

Genetic diversity among Borrelia strains determined by single-strand conformation polymorphism analysis of the ospC gene and its association with invasiveness.

Journal of clinical microbiology - 1 Nov 2003

Lagal Vanessa, Postic Danièle, Ruzic-Sabljic Eva, Baranton Guy

Abstract excerpt

Lyme borreliosis (LB) is a tick-borne spirochetal infection caused by three Borrelia species: Borrelia afzelii, B. garinii, and B. burgdorferi sensu stricto. LB evolves in two stages: a skin lesion called erythema migrans and later, different disseminated forms (articular, neurological, cardiac.). Previous research based on analysis of ospC sequences allowed the definition of 58 groups (divergence of <2% within a...

Topics

Antigens, Bacterial
Bacterial Outer Membrane Proteins
Borrelia
Borrelia burgdorferi
Borrelia burgdorferi Group
Europe
Genetic Variation
Humans
Japan
Lyme Disease
Phylogeny

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single-Stranded Conformational

United States

Source

Open in PubMed Open full text

Identifiers

PMID: 14605139
DOI: 10.1128/JCM.41.11.5059-5065.2003
PMCID: PMC262544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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