Article
The vit gene maps to the mi (microphthalmia) locus of the laboratory mouse.
The Journal of heredity - 1 Jan 2000
Lamoreux M L, Boissy R E, Womack J E, Nordlund J J
Abstract excerpt
The murine model for human vitiligo (the vit/vit mouse) develops progressive depigmentation of the pelage, skin, and eyes. The vit gene is inherited as an autosomal recessive. We have used classical breeding and isozyme marker analysis to map this vit gene that produces a vitiligo-like condition...
Topics
- Alleles
- Animals
- Chromosome Mapping
- Genetic Markers
- Isoenzymes
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Microphthalmos
- Vitiligo