Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insight into the microphthalmia gene.

Trends in genetics : TIG - 1 Nov 1995

Moore K J

Abstract excerpt

The murine microphthalmia gene (mi) is one of the last multi-allelic, classic coat-colour genes to be cloned in the mouse and, similar to many of these genes, encodes an exciting molecule that is is involved in multiple developmental processes. The existence of the numerous alleles has allowed the molecular dissection of the function of the MI bHLH-Zip transcription factor in vivo and offers a unique opportunity...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to DNA-Binding Proteins
Share to Hair Color

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Microphthalmos

Share to Mutation

Share to Transcription Factors

Source

Identifiers

PMID: 8578601
DOI: 10.1016/s0168-9525(00)89143-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insight into the microphthalmia gene.PMID 8578601Read ↗

Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein.Semantic proximity Read ↗

Molecular basis of mouse microphthalmia (mi) mutations helps explain their developmental and phenotypic consequences.Semantic proximity Read ↗

Interpretation of complex phenotypes: lessons from the Mitf gene.Semantic proximity Read ↗

microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family.Semantic proximity Read ↗

Melanocytes and the microphthalmia transcription factor network.Semantic proximity Read ↗

Genomic, transcriptional and mutational analysis of the mouse microphthalmia locus.Semantic proximity Read ↗

The novel mouse microphthalmia mutations Mitfmi-enu5 and Mitfmi-bcc2 produce dominant negative Mitf proteins.Semantic proximity Read ↗

Genomic analysis of the Microphthalmia locus and identification of the MITF-J/Mitf-J isoform.Semantic proximity Read ↗

Microphthalmia-associated transcription factor (MITF): multiplicity in structure, function, and regulation.Semantic proximity Read ↗

The semidominant Mi(b) mutation identifies a role for the HLH domain in DNA binding in addition to its role in protein dimerization.Semantic proximity Read ↗

Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently.Semantic proximity Read ↗

Microphthalmia cloudy-eye (mi(ce)): a new murine allele.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.