[The expression of the mutant gene mi in mouse aggregation chimeras].

Abstract excerpt

Using aggregation of 8-cell embryos belonging to two mouse strains, we produced 17 chimeras, mi/mi<==>+/+ (3 organisms), mi/+<==>+/+ (9 organisms), and +/+<==>+/+ (5 organisms), that achieved the age of 30 days. Chimerism was identified by mosaic pigmentation of coat and retinal pigment epithelium (RPE). All mi/mi<==>+/+ chimeras suffered from microphthalmia. Disturbances of eye development in these mice were...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Alleles
• Share to Gene Expression Regulation
• Share to Genotype