Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Helicobacter pylori stimulates host vascular endothelial growth factor‐A ( vegf‐A ) gene expression via MEK/ERK‐dependent activation of Sp1 and Sp3

3 Nov 2003

Abstract excerpt

VEGF-A is a key regulator of inflammatory and tumor-associated angiogenesis. H. pylori plays a critical role in the pathogenesis of benign and malignant gastric diseases. It has been suggested that H. pylori infection is associated with activation of host angiogenesis, however, underlying mechanisms as well as angiogenic growth factors activated by the bacterium have not yet been identified. Therefore, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Galectins and Cancer Biology
Share to Helicobacter pylori-related gastroenterology studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 14597566
DOI: 10.1096/fj.03-0055fje

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Helicobacter pylori stimulates host vascular endothelial growth factor‐A ( vegf‐A ) gene expression via MEK/ERK‐dependent activation of Sp1 and Sp3PMID 14597566Read ↗

Altered expression of transcription factor Sp1 critically impacts the angiogenic phenotype of human gastric cancer.Semantic proximity Read ↗

Helicobacter pylori urease induces pro‐inflammatory effects and differentiation of human endothelial cells: Cellular and molecular mechanismSemantic proximity Read ↗

Modulation of Host Angiogenesis as a Microbial Survival Strategy and Therapeutic TargetSemantic proximity Read ↗

Novel single nucleotide polymorphism of the VEGF gene as a risk predictor for gastroduodenal ulcers.Semantic proximity Read ↗

<i>Helicobacter pylori</i>stimulates host cyclooxygenase-2 gene transcription: critical importance of MEK/ERK-dependent activation of USF1/-2 and CREB transcription factorsSemantic proximity Read ↗

The interleukin-8-251 AA genotype is associated with angiogenesis in gastric carcinogenesis in Helicobacter pylori-infected Koreans.Semantic proximity Read ↗

Association between Expression of Transcription Factor Sp1 and Increased Vascular Endothelial Growth Factor Expression, Advanced Stage, and Poor Survival in Patients with Resected Gastric CancerSemantic proximity Read ↗

A positive feedback loop between STAT3 and cyclooxygenase‐2 gene may contribute to Helicobacter pylori‐associated human gastric tumorigenesisSemantic proximity Read ↗

hTERT promotes tumor angiogenesis by activating VEGF via interactions with the Sp1 transcription factorSemantic proximity Read ↗

Expression of endothelial nitric oxide synthase correlates with the angiogenic phenotype of and predicts poor prognosis in human gastric cancer.Semantic proximity Read ↗

Helicobacter pylori Activates Mitogen-activated Protein Kinase Cascades and Induces Expression of the Proto-oncogenes c-fos and c-junSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.