Article
Expression of endothelial nitric oxide synthase correlates with the angiogenic phenotype of and predicts poor prognosis in human gastric cancer.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Jan 2005
Wang Liwei, Shi Gary G, Yao James C, Gong Weida, Wei Daoyan, Wu Tsung-Teh, Ajani Jaffer A, Huang Suyun, Xie Keping
Abstract excerpt
BACKGROUND: Angiogenesis is a critical aspect of cancer biology and is subject to regulation by multiple molecular pathways. We evaluated the expression of nitric oxide synthase (NOS) III and its relationship with the angiogenic phenotype and expression of the transcription factor Sp1, as well as their effect on survival in patients with gastric cancer. METHODS: The NOS III expression level and tumor microvessel...
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