Article
The interleukin-8-251 AA genotype is associated with angiogenesis in gastric carcinogenesis in Helicobacter pylori-infected Koreans.
Cytokine - 1 Aug 2010
Song Ji Hyun, Kim Sang Gyun, Jung Sung-Ae, Lee Mi Kyoung, Jung Hyun Chae, Song In Sung
Abstract excerpt
Helicobacter pylori (H. pylori) is an important risk factor of gastric adenocarcinoma. Interleukin (IL)-8 is a potent angiogenic factor and plays an important role in inflammation of gastric mucosa by H. pylori. Host susceptibility may help to predict H. pylori-infected individuals with a higher risk of gastric adenocarcinoma. The aim of this study was to clarify the effect of IL-8 polymorphism on angiogenesis in...
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