Article
DOK, a cell line established from human dysplastic oral mucosa, shows a partially transformed non-malignant phenotype.
International journal of cancer - 2 Dec 1992
Chang S E, Foster S, Betts D, Marnock W E
Abstract excerpt
There are many reports of cell lines being established from human oral squamous-cell carcinomas but apparently none of cell lines from dysplastic or "pre-malignant" oral mucosa. We describe here the isolation and characterization of a cell line, DOK (dysplastic oral keratinocyte), from a piece of dorsal tongue showing epithelial dysplasia. The tissue was obtained from a 57-year-old man who was a heavy smoker...
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