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Article

The phenotype of in vitro reconstituted normal human oral epithelium is essentially determined by culture medium.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Apr 2005

Costea Daniela Elena, Dimba Anne Okumo Elizabeth, Loro Lado Lako, Vintermyr Olav Karsten, Johannessen Anne Christine

Abstract excerpt

OBJECTIVE: To evaluate the role of various culture media and serum supplement on growth of oral cells in monolayer, and on morphogenesis of in vitro reconstituted normal human oral epithelium. METHODS: Primary keratinocytes and fibroblasts were isolated from normal human buccal mucosa. The monolayers were assessed by growth curve analysis and morphology. The organotypic cultures were evaluated by morphometry,...

Topics

Blood
Cell Death
Cell Differentiation
Cells, Cultured
Culture Media
Epithelium
Fibroblasts
Humans
Immunohistochemistry
In Situ Nick-End Labeling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Keratinocytes

Morphogenesis

Mouth Mucosa

Phenotype

Tissue Culture Techniques

Source

Identifiers

PMID: 15752261
DOI: 10.1111/j.1600-0714.2005.00308.x

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