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Article

Apoptosis of terminal hypertrophic chondrocytes in an in vitro model of endochondral ossification.

The Journal of pathology - 1 Nov 2003

Cheung J O P, Grant M E, Jones C J P, Hoyland J A, Freemont A J, Hillarby M C

Abstract excerpt

It is widely accepted that growth plate chondrocytes undergo apoptosis when they reach the terminal hypertrophic stage of their differentiation during the process of endochondral ossification in vivo. In this report, an established chondrocyte cell culture model of mammalian endochondral ossification was utilized to investigate the fate of chondrocytes after they had entered hypertrophy in vitro. Fetal bovine...

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Identifiers

PMID: 14595763
DOI: 10.1002/path.1462

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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