Active role of chondrocyte apoptosis in endochondral ossification

Abstract excerpt

Endochondral ossification involves an ordered progression from cell division through hypertrophic differentiation to cell death. The apoptotic nature of chondrocyte death was first suggested by characteristic changes in morphology; and more recently by the pattern of DNA fragmentation and other characteristic features of apoptosis. In situ detection, although controversial, suggests that DNA fragmentation...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bone Metabolism and Diseases
• Share to Cell Adhesion Molecules Research
• Share to Osteoarthritis Treatment and Mechanisms