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Article

Population genetics of polymorphism and divergence.

Genetics - 1 Dec 1992

Sawyer S A, Hartl D L

Abstract excerpt

Frequencies of mutant sites are modeled as a Poisson random field in two species that share a sufficiently recent common ancestor. The selective effect of the new alleles can be favorable, neutral, or detrimental. The model is applied to the sample configurations of nucleotides in the alcohol dehydrogenase gene (Adh) in Drosophila simulans and Drosophila yakuba. Assuming a synonymous mutation rate of 1.5 x 10(-8)...

Topics

Alcohol Dehydrogenase
Alleles
Animals
Base Sequence
Drosophila
Genetics, Population
Mutation
Poisson Distribution
Polymorphism, Genetic
Sequence Alignment
Species Specificity

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Identifiers

PMID: 1459433
DOI: 10.1093/genetics/132.4.1161
PMCID: PMC1205236

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1459433-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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