The distribution of the number of mutations in the genealogy of a sample from a single population.

doi:10.1016/j.tpb.2025.08.001

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Article

The distribution of the number of mutations in the genealogy of a sample from a single population.

Theoretical population biology - 1 Oct 2025

Fu Yun-Xin

Abstract excerpt

The number K of mutations in the genealogy of a sample of n sequences from a single population is one essential summary statistic in molecular population genetics and is equal to the number of segregating sites in the sample under the infinite-sites model. Although its expectation and variance are the most widely utilized properties, its sampling formula (i.e., probability distribution) is the foundation for all...

Topics

Mutation
Genetics, Population
Models, Genetic
Sequence Analysis, DNA

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Open in PubMed

Identifiers

PMID: 40876600
DOI: 10.1016/j.tpb.2025.08.001

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