Screening and mutagenesis of Aspergillus niger for the improvement of glucose 6-phosphate dehydrogenase production.

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Article

Screening and mutagenesis of Aspergillus niger for the improvement of glucose 6-phosphate dehydrogenase production.

Prikladnaia biokhimiia i mikrobiologiia - 1 Jan 2000

Liu Jian-Zhong, Zhang Qian-Ling, Weng Li-Ping, Ji Liang-Nian

Abstract excerpt

The strain of Aspergillus niger ZBY-7 was selected as the original strain of glucose 6-phosphate dehydrogenase production. After mutagenesis of the strain using UV irradiation and nitrosoguanidine, mutants of Aspergillus niger resistant to certain metabolic inhibitor were obtained. Five of the mutants showed increased glucose 6-phosphate dehydrogenase production. The mutant resistant to antimycin A (Aspergillus...

Topics

Antifungal Agents
Antimycin A
Aspergillus niger
Drug Resistance, Multiple, Fungal
Enzyme Inhibitors
Glucosephosphate Dehydrogenase
Industrial Microbiology
Mutagenesis
Mutation
Nitrosoguanidines
Ultraviolet Rays
Up-Regulation

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Open in PubMed

Identifiers

PMID: 14593870

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