Article
Evidence for antagonistic regulation of cell growth by the calcineurin and high osmolarity glycerol pathways in Saccharomyces cerevisiae.
The Journal of biological chemistry - 30 Jan 2004
Shitamukai Atsunori, Hirata Dai, Sonobe Shinya, Miyakawa Tokichi
Abstract excerpt
Because Ca(2+) signaling of budding yeast, through the activation of calcineurin and the Mpk1/Slt2 mitogen-activated protein kinase cascade, performs redundant function(s) in the events essential for growth, the simultaneous deletion of both these pathways (Delta cnb1 Delta mpk1) leads to lethali...
Topics
- Actins
- Calcineurin
- Calcium
- Cell Cycle
- Cell Division
- Cell Separation
- DNA, Complementary
- DNA-Binding Proteins
- Flow Cytometry
- G2 Phase
- Gene Deletion
- Genotype
- Glycerol
- Microscopy, Fluorescence
- Mitogen-Activated Protein Kinases
- Mitosis
- Models, Biological
- Mutation