Article
High levels of chromosomal imbalances in typical and small-cell variants of T-cell prolymphocytic leukemia.
Cancer genetics and cytogenetics - 1 Nov 2003
Costa Dolors, Queralt Rosa, Aymerich Marta, Carrió Ana, Rozman María, Vallespí Teresa, Colomer Dolors, Nomdedeu Benet, Montserrat Emili, Campo Elías
Abstract excerpt
T-cell prolymphocytic leukemia (T-PLL) is a rare postthymic T-cell disorder that may show different morphologic variants and a very aggressive clinical behavior. On occasion, patients may present with an indolent clinical course and long survival. The disease is genetically characterized by the presence of complex karyotypes with recurrent alterations involving chromosomes 8, 14, and 11. The possible relationship...
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