Article
Trisomy 8q due to i(8q) or der(8) t(8;8) is a frequent lesion in T‐prolymphocytic leukaemia: four new cases and a review of the literature
1 Apr 1994
Abstract excerpt
Cytogenetic abnormalities found in four cases of T-cell prolymphocytic leukaemia (T-PLL) are described. An isochromosome 8q was found in three patients and a t(8;8) in one. In the four cases, karyotypes were complex and showed a high degree of instability. In addition, we reviewed 27 published cases of cytogenetically studied T-PLL. On the whole, the most frequently recurring anomalies in T-PLL are 14q lesions...
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