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Article

Telomere and ribosomal DNA repeats are chromosomal targets of the bloom syndrome DNA helicase.

BMC cell biology - 27 Oct 2003

Schawalder James, Paric Enesa, Neff Norma F

Abstract excerpt

BACKGROUND: Bloom syndrome is one of the most cancer-predisposing disorders and is characterized by genomic instability and a high frequency of sister chromatid exchange. The disorder is caused by loss of function of a 3' to 5' RecQ DNA helicase, BLM. The exact role of BLM in maintaining genomic integrity is not known but the helicase has been found to associate with several DNA repair complexes and some DNA...

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Source

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Identifiers

PMID: 14577841
DOI: 10.1186/1471-2121-4-15
PMCID: PMC270065

Genes

BLM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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