Article
Yeast Nap1-binding protein Nbp2p is required for mitotic growth at high temperatures and for cell wall integrity.
Genetics - 1 Oct 2003
Ohkuni Kentaro, Okuda Asuko, Kikuchi Akihiko
Abstract excerpt
Nbp2p is a Nap1-binding protein in Saccharomyces cerevisiae identified by its interaction with Nap1 by a two-hybrid system. NBP2 encodes a novel protein consisting of 236 amino acids with a Src homology 3 (SH3) domain. We showed that NBP2 functions to promote mitotic cell growth at high temperatures and cell wall integrity. Loss of Nbp2 results in cell death at high temperatures and in sensitivity to calcofluor...
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