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Article

Growth rate regulation of lac operon expression in Escherichia coli is cyclic AMP dependent.

FEBS letters - 23 Oct 2003

Kuo Jong-Tar, Chang Yu-Jen, Tseng Ching-Ping

Abstract excerpt

In contrast to the ribosomal RNA gene expression increasing with growth rate, transcription of the lac operon is downregulated by cell growth rate. In continuous culture, growth rate regulation of lac promoter was independent of carbon substrate used and its location on the chromosome. Since the lac operon is activated by cyclic adenosine monophosphate (cAMP), which decreases with increasing cell growth rate,...

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Identifiers

PMID: 14572658
DOI: 10.1016/s0014-5793(03)01071-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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