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Elusive Roles of the Different Ceramidases in Human Health, Pathophysiology, and Tissue Regeneration.

Cells - 2 Jun 2020

Duarte Carolina, Akkaoui Juliet, Yamada Chiaki, Ho Anny, Mao Cungui, Movila Alexandru

Abstract excerpt

Ceramide and sphingosine are important interconvertible sphingolipid metabolites which govern various signaling pathways related to different aspects of cell survival and senescence. The conversion of ceramide into sphingosine is mediated by ceramidases. Altogether, five human ceramidases-named acid ceramidase, neutral ceramidase, alkaline ceramidase 1, alkaline ceramidase 2, and alkaline ceramidase 3-have been...

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Identifiers

PMID: 32498325
DOI: 10.3390/cells9061379
PMCID: PMC7349419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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