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Article

Bax is essential for mitochondrion-mediated apoptosis but not for cell death caused by photodynamic therapy

1 Oct 2003

Abstract excerpt

The role of Bax in the release of cytochrome c from mitochondria and the induction of apoptosis has been demonstrated in many systems. Using immunocytochemical staining, we observed that photodynamic therapy (PDT) with the photosensitiser Pc 4 induced Bax translocation from the cytosol to mitochondria, and the release of cytochrome c from mitochondria as early signalling for the intrinsic pathway of apoptosis in...

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Share to Bioactive Compounds and Antitumor Agents
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Identifiers

PMID: 14562036
DOI: 10.1038/sj.bjc.6601298

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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