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Article

Involvement of apolipoprotein E in glioblastoma: immunohistochemistry and clinical outcome.

Neuroreport - 27 Oct 2003

Nicoll James A R, Zunarelli Elena, Rampling Roy, Murray Lilian S, Papanastassiou Vakis, Stewart Janice

Abstract excerpt

We hypothesised that apolipoprotein E (apoE) influences brain tumours by delivery of lipids to tumour cells and by analogy with other brain insults. APOE gene analysis was performed for 126 glioblastomas, the commonest primary brain tumour. Neither APOE epsilon2 nor epsilon4 alleles were significantly associated with differences in post-operative survival. However, there was apoE immunoreactivity of tumour cells,...

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Source

Identifiers

PMID: 14561921
DOI: 10.1097/00001756-200310270-00008

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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