Article
Differentiation of human basophils: an overview of recent advances and pending questions.
Journal of leukocyte biology - 1 Apr 2002
Arock Michel, Schneider Elke, Boissan Mathieu, Tricottet Viviane, Dy Michel
Abstract excerpt
Basophils are rare, circulating leukocytes derived from hematopoietic CD34+ progenitors. The identification of cytokines promoting their development in vitro has led to substantial advances in understanding their differentiation process. An important role could be assigned to interleukin-3 (IL-3), which supports the maturation of hematopoietic progenitors into basophils in vitro and in vivo. In contrast to other...
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