Article
Regulation of the human leukemia inhibitory factor gene by ETS transcription factors.
Neuroimmunomodulation - 1 Jan 2004
Bamberger Ana-Maria, Jenatschke Susanne, Schulte Heinrich M, Ellebrecht Iring, Beil Frank Ulrich, Bamberger Christoph M
Abstract excerpt
OBJECTIVES: Leukemia inhibitory factor (LIF) is a pleiotropic cytokine mainly produced by activated T lymphocytes. We previously demonstrated that human Jurkat T lymphoma cells represent a valid model of LIF gene expression. This study was designed to identify regions critical for LIF promoter activation in Jurkat cells. METHODS: Luciferase constructs under the control of different portions of the human LIF...
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