Article
Temperature requirements for initiation of RNA-dependent RNA polymerization.
Virology - 30 Sept 2003
Yang Hongyan, Gottlieb Paul, Wei Hui, Bamford Dennis H, Makeyev Eugene V
Abstract excerpt
To continue the molecular characterization of RNA-dependent RNA polymerases of dsRNA bacteriophages (Cystoviridae), we purified and biochemically characterized the wild-type (wt) and a temperature-sensitive (ts) point mutant of the polymerase subunit (Pol) from bacteriophage phi12. Interestingly,...
Topics
- Bacteriophage phi 6
- Cystoviridae
- Gene Expression Regulation, Viral
- Models, Molecular
- Mutation
- RNA, Double-Stranded
- RNA, Viral
- RNA-Dependent RNA Polymerase
- Temperature
- Templates, Genetic
- Transcription, Genetic
- Virus Replication