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Article

Acidic pH is required for the functional assembly of the type III secretion system encoded by Salmonella pathogenicity island 2.

FEMS microbiology letters - 26 Sept 2003

Rappl Catherine, Deiwick Jörg, Hensel Michael

Abstract excerpt

Salmonella enterica employs two type III secretion systems (T3SS) for interactions with host cells during pathogenesis. The T3SS encoded by Salmonella pathogenicity island 2 (SPI2) is required for the intracellular replication of Salmonella and the survival inside phagocytes. During growth in vitro, acidic pH is a signal that promotes secretion of proteins by this T3SS. We analyzed protein levels and subcellular...

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PMID: 14553934
DOI: 10.1016/S0378-1097(03)00638-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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