Article
Role of the Salmonella pathogenicity island 1 (SPI-1) protein InvB in type III secretion of SopE and SopE2, two Salmonella effector proteins encoded outside of SPI-1.
Journal of bacteriology - 1 Dec 2003
Ehrbar Kristin, Friebel Andrea, Miller Samuel I, Hardt Wolf-Dietrich
Abstract excerpt
Salmonella enterica subspecies 1 serovar Typhimurium encodes a type III secretion system (TTSS) within Salmonella pathogenicity island 1 (SPI-1). This TTSS injects effector proteins into host cells to trigger invasion and inflammatory responses. Effector proteins are recognized by the TTSS via signals encoded in their N termini. Specific chaperones can be involved in this process. The chaperones InvB, SicA, and...
Topics
- Animals
- Bacterial Proteins
- Biological Transport
- COS Cells
- Chlorocebus aethiops
- Guanine Nucleotide Exchange Factors
- Molecular Chaperones
- Mutation
- Salmonella enterica
- Salmonella typhimurium
- Virulence