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Article

Tumor-derived aberrant methylation in plasma of invasive ductal breast cancer patients: clinical implications.

Oncology reports - 1 Jan 2000

Hu Xi-Chun, Wong Ivy H N, Chow Louis W C

Abstract excerpt

Progressive p16 methylation has been associated with metastasis and invasive phenotypes in many cancers. Loss of E-cadherin (CDH1) function contributes to breast cancer progression by promoting cell proliferation, invasion and metastasis. Using methylation-specific PCR, aberrant hypermethylation of p16 and CDH1 in tumor and plasma was analyzed and correlated with levels of serum protein markers, carcinoembryonic...

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Identifiers

PMID: 14534701

Genes

CDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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