Article
Tumor-derived aberrant methylation in plasma of invasive ductal breast cancer patients: clinical implications.
Oncology reports - 1 Jan 2000
Hu Xi-Chun, Wong Ivy H N, Chow Louis W C
Abstract excerpt
Progressive p16 methylation has been associated with metastasis and invasive phenotypes in many cancers. Loss of E-cadherin (CDH1) function contributes to breast cancer progression by promoting cell proliferation, invasion and metastasis. Using methylation-specific PCR, aberrant hypermethylation...
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