Article
Single-nucleotide polymorphisms of TNFA and IL1 in allergic rhinitis.
Journal of investigational allergology & clinical immunology - 1 Jan 2013
Nasiri R, Amirzargar A Akbar, Movahedi M, Hirbod-Mobarakeh A, Farhadi E, Behniafard N, Tavakkol M, Ansaripour B, Moradi B, Zare A, Rezaei N
Abstract excerpt
BACKGROUND: Allergic rhinitis is a complex polygenic disorder of the upper respiratory tract. Given that proinflammatory cytokines such as tumor necrosis factor (TNF) and interleukin (IL) 1 seem to play a role in the development of allergic rhinitis, we evaluated the associations between various single-nucleotide polymorphisms (SNPs) of the TNF and IL1 genes in a case-control study. METHODS: The study population...
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